Transcriptional profile of the Trichoderma reesei ace3 deletion mutant cultured in the presence of lactose

To address why ace3 inactivation strains could not grow in lactose, and to further explore the function of ACE3, the full genomic responses of the parental strain QM6a (wild-type, WT) and ACE3 deletion strain (Δace3) and were assessed by RNA sequencing (RNA-Seq) to profile the genome-wide mRNA abundance observed following lactose addition (12 hours after transfer into a 2% lactose solution).