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Demography and clinical history of SCA subjects with and without PHT.

Figshare2017-09-15 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Demography_and_clinical_history_of_SCA_subjects_with_and_without_PHT_/5408095 数据链接链接失效反馈

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资源简介：

Demography and clinical history of SCA subjects with and without PHT.

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创建时间：

2017-09-15

肺动脉高压

衰老细胞清除

To explore the role played by senescent cells in mice models of pulmonary hypertension we exposed young C57BL6/j mice to 8 days hypoxia or normoxia and treated with senolytic drug ABT-263 (50mg/kg/day

NIAID Data Ecosystem90

Fcer1a全身敲除并建立低氧诱导小鼠肺动脉高压模型实验数据集

肺动脉高压

免疫学

全身敲除Fcer1a后建立低氧诱导肺动脉高压模型，对照组小鼠为WT小鼠。低氧建模4周后在体进行心动超声检测，测量小鼠肺动脉血流多普勒。随后取材检测小鼠RVSP，RVHI，病理衡量小鼠肺血管厚度和肌化程度。实验结果显示敲除IgE受体Fcer1a可以缓解低氧所致肺动脉高压和肺血管重塑。

国家人口健康科学数据中心30

Correlations with clinical parameters (Spearman r and p-value) for n = 24 patients.

肺动脉高压

肺功能参数

mPAP: mean pulmonary arterial pressure, PVR: pulmonary vascular resistance, AVDO2: arterial-venous difference in oxygen content, art SO2: arterial oxygen saturation, ven SO2: venous oxygen saturation,

NIAID Data Ecosystem20

Correlations between OUE and key abnormal parameters for IPAH patients (N = 32).

肺动脉高压

生理参数关联分析

*P<0.05, **P<0.005. The abbreviation definitions are same as Table 1.

NIAID Data Ecosystem30

Verification of the hypoxia-induced PAH model in rats in this study.

肺动脉高压

低氧生理实验

Norm: normal group n = 10, Hypo: Hypoxia group n = 10; RVSP: Right ventricular systolic pressure, mPAP mean pulmonary artery pressure, RV/(LV+S): right ventricle to left ventricle plus septum. Table 1

NIAID Data Ecosystem30

Demography and clinical history of SCA subjects with and without PHT.

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