NANOS2-binding regulates mRNA half-life and key spermatogonial stem cell self-renewal pathways
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We have identified NANOS2 bound targets transcriptome wide by employing CRAC and RNA-seq in mouse SSCs. We have determined the average mRNA half-life in SSCs by SLAM-seq. By comparing CRAC and SLAM-seq datasets, we have demonstrated that NANOS2 binding reduces mRNA stability in SSCs.
创建时间：
2022-02-20
