Parameter estimates, log-likelihood values and selective pressures across codons for P. falciparum glycerol kinase under models of variable �� ratios.

Models were implemented with the codeml algorithm in the PAML package. Under the M2 model, there were >300 codons with ��99% (not listed in table). These were subjected to the SLR test for further categorization of the intensity of purifying selection (see text). There were 21 neutral or positively selected sites (�ء�1) with a Bayes Empirical Bayes (BEB) posterior probability of >50%, although none of these were statistically significant at 95%. Under the M8 model, no statistically significant positively selected sites were identified. For M7 and M8, p and q are the shape parameters of the �� distribution. ? = log-likelihood estimate, �� = transition/transversion ratio, p = BEB posterior probability. Numbering corresponds to the sequence alignment in Figure 3.