Transcription profiling by array of spleen samples from male and female BWF1 lupus-prone mice to investigate sex hormone regulated genes

Goal of experiment: Identification of differentially expressed immune genes from male and female BWF1 lupus-prone mice. (Female incidence is higher than male--attempting to find sex hormone regulated genes that may contribute to this difference).实验目标：从雄性与雌性BWF1狼疮易感小鼠中鉴定差异表达免疫基因。（雌性发病率高于雄性——本研究拟探寻可能促成该性别差异的、受性激素调控的基因。）