SSTR2 in non-function and well-differentiated pNET

From June 2014 to January 2021, all non-functional pNET patients undergoing surgical resection with confirmed pathological results at Fudan University Shanghai Cancer Center (FUSCC) single center were retrospectively reviewed and 223 non-function and well-differentiated cases of pNET were enrolled in our cohort. Clinicopathological information was collected via the medical record database and pathologic examination notes. Expression of SSTR2 was detected via immunohistochemical staining of paraffin-embedded tissues with antibodies against SSTR2 according to standard IHC procedures. clinicopathological data was provided. Additionally, we report of rare case of multifocal pNET lesion with different SSTR2 status and we perform whole-exome sequencing on the two tumors. Sequencing results and variations after deduction of normal tissue were provided.