Study of the correlation between endophyte abundances and metabolite levels in different tissue parts of cultivated and wild Arnebia euchroma (Royle) Johnst based on microbiome analysis and metabolomics.

In summary, the endophytic community diversity of cultivated A. euchroma was different from that of wild A. euchroma, and the endophytes presented tissue specificity in A. euchroma. Proteophyta, Cyanophyta, Ascomycetes and Basidiomycetes were the dominant endophytes in the A. euchroma samples. The A. euchroma metabolites exhibited tissue specificity, and there was no significant difference in metabolites between cultivated and wild A. euchroma. Various metabolites of A. euchroma were positively and negatively correlated with dominant endophytes, and the main active substances of A. euchroma were also significantly correlated with endophytes, which provides an important basis for exploring microbial,metabolite,host,plant interactions and is highly important for mining beneficial microbial resources from A. euchroma.