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Crystal structure of the catalytic domain of FGFR1 kinase in complex with ARQ 069

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Crystal structure of the catalytic domain of FGFR1 kinase in complex with ARQ 069 Descriptor: (6S)-6-phenyl-5,6-dihydrobenzo[h]quinazolin-2-amine, 1,2-ETHANEDIOL, Basic fibroblast growth factor receptor 1, ... Authors: Eathiraj, S, Palma, R, Hirschi, M, Volckova, E, Nakuci, E, Castro, J, Chen, C.R, Chan, T.C, France, D.S, Ashwell, M.A. Deposit date: 2011-04-12 Release date: 2011-05-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.01 Å) Cite: A novel mode of protein kinase inhibition exploiting hydrophobic motifs of autoinhibited kinases: discovery of ATP-independent inhibitors of fibroblast growth factor receptor. J.Biol.Chem., 286, 2011
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2011-04-12
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