ChIP-seq BHT-101 cells and BHT-101 ASH1L KO cell lines
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE147074
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资源简介：
The goal of this study is to assess the role of ASH1 like histone lysine methyltransferase (ASH1L) in the biology of anaplastic thyroid cancer. CRISPR-Cas9 was used to create cell lines derived from BHT-101 anaplastic thyroid cancer cells with premature stop codons prior to the catalytic domain within both alleles of ASH1L. ChIP-seq for H3K36me2, the histone mark catalyzed by ASH1L, was performed on two KO cell lines, and compared to wild type BHT-101 cells. H3K36me2 ChIP-seq was performed on wild type BHT-101 cells and 2 BHT-101 ASH1L KO cell lines. Three biological replicates were performed and analyzed.
创建时间：
2020-05-14
