Frequency and timing of adverse drug events by # weekly evaluations and reaction type.

1No severe dermatologic reactions occurred in this cohort.
2Only one severe gastrointestinal reaction occurred in this cohort (anorexia with weight loss). This was grouped with the moderate reactions for this analysis.
3No moderate neurologic reactions occurred in this cohort. Mild ADEs included peripheral neuropathy with persistent that did not alter function. Severe ADEs included altered taste or smell, with or without persistent peripheral neuropathy.