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Proteomic profiling of nuclear fractions of SMARCA4 knockdown samples in HDMB03

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NIAID Data Ecosystem2026-05-10 收录
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SMARCA4 mutations are common in Medulloblastoma but not much is understood about its pathobiology. In this study we prepared SMARCA4 knockdown models using a Group 3 medulloblastoma cell line called HDMB03 and investigated the proteomic changes. Nuclear enrichment was performed using hypertonic and hypotonic buffers. The nuclear enriched fractions were analysed on LC-MS/MS.

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2026-03-25
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