Mouse Data_traumatic_nerve_injury_and_healthy_mice.xlsx

Quantitative scoring enabling comparison of neuromotor recovery in peripheral nerve injury models is critical to understanding and gauging the extent of injury and repair. Not all interventions can be experimented in humans. However, methods for evaluating rodent gait lack the multivariate description applied to humans limiting their effectiveness. Using state of the art methods to multivariately evaluate novel therapies (like limb transplantation) in murine gait models represents a novel clinical problem to investigate.Video gait data was collected of mice walking on the DigiGait treadmill system across groups representing increasing degrees of damage to the neuro-musculo-skeletal sequence of healthy gait. Groups included healthy controls and two experimental groups: (a) total nerve transection + reconnection of the femoral and sciatic nerves, and (b) nerve, muscle, and bone damage via total hind limb transplantation.