We have previously reported that Mycobacterium tuberculosis Rv2837c (cnpB) encodes a phosphodiesterase that specifically cleaves cyclic di-AMP (c-di-AMP) into AMP. Deletion of cnpB results in signific
Molecular analysis of DNA repair mechanisms in Mycobacterium tuberculosis. Bacteria exposed to mitomycin C, UV irradiation or hydrogen perxoxide treatment for up to 12 hours. Keywords: repeat sample
Triplicate 10mL cultures of M. tuberculosis grown in Sautons media without detergent in planktonic (exponential growth phase at OD600 0.2) compared to pellicle (3 weeks growth without shaking in 5% CO