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Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor 11

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Protein Data Bank Japan2024-11-13 更新2026-04-11 收录
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Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor 11 Descriptor: 3C-like proteinase nsp5, GLYCEROL, benzyl {(3S)-1-[(2S)-1-({(2S,3R)-4-(cyclopropylamino)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-5-oxopyrrolidin-3-yl}carbamate Authors: Sacco, M, Chen, Y. Deposit date: 2022-08-06 Release date: 2023-04-05 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Development of the Safe and Broad-Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained alpha , gamma-AA Peptide Scaffold. Chemistry, 29, 2023
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2022-08-06
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