RNA sequencing/Gene expression studies of G⍺13 signaling in lymphoma [scRNA-seq]

We determined that loss of G⍺13 signaling promotes oncogenic signaling in aggressive B-cell lymphomas. We sought to measure gene expression change in control and G⍺13-deficient germinal center (GC) B cells by RNA-sequencing Mesenteric LN (mLN) and peripheral LN (pLN) GC B cells from control and G⍺13-deficient mice were isolated by Fluorescence-activated cell sorting (FACS) and analyzed using scRNAseq ***Submitter declares that the raw data will be deposited in SRA*** Additonal information can be found at: https://lymphochip.nih.gov/local/GNA13_Proliferation/