Genes shared between P. falciparum and P. vivax but absent in P. knowlesi.

Shown are all P. falciparum genes that were found to have a syntenic ortholog in the second human parasite P. vivax but no identifiable ortholog (neither syntenic nor non-syntenic) in the monkey parasite P. knowlesi. Four of these genes (MAL8P1.126, MAL13P1.107, PFL0360c, and PF14_0236) also lack an identifiable ortholog in the three rodent parasite genomes and are thus potentially unique to human Plasmodium parasites. Genes ordered and grouped by similarity of their IDC expression profile (see legend Table 1). A table with graphical RNA-seq expression profiles for these genes is provided in Table S10. Abbreviations: Pf: P. falciparum; Pv: P. vivax; PvPID: global protein sequence identity with P. vivax ortholog; OG: closest OrthoMCL DB species out-group with predicted ortholog of this gene; ALVE: Alveolates; RODE: rodent malaria parasites; iRBCm: infected red blood cell membrane (PIESPs)/Schizont; SZ: sporozoites; (el)GC: (early/late) gametocytes; TZ: trophozoite; MZ: merozoites; SC: schizont; ZF: zinc finger domain; TM: predicted transmembrane domain; SP: predicted signal peptide.