Average volumes of BBB disruption and T2-enhancement.

*Column 3: Enhancing volume on T1W images at the day of the treatment, representing the volume of BBB disruption (mean±SE).**Column 4: Enhancing volume on T2W images at the day of the treatment, representing initial tissue response to treatment (mean±SE).***Column 5: Ratio of enhancing volume on T2W and T1W images on Day 0, showing that BBB disruption volume was always larger than tissue damage volume (mean±SE).****Column 6: Ratio of enhancing volume on T2W images 24–48 hours post treatment and T2W images on Day 0, showing the tissue response volume significantly increased in the first 2 days post treatment (mean±SE).****Column 7: Ratio of enhancing volume on T2-weighted MRI 3 weeks post treatment, representing the permanent tissue damage, and T1-weighted enhancing volume on Day 0, showing that BBB disruption was always larger than the permanent tissue damage (mean±SE).