Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis

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Repairing broken chromosomes via joint molecule (JM) intermediates is hazardous and therefore strictly controlled in most organisms

借助联合分子（joint molecule, JM）中间体修复断裂染色体的过程具有危害性，故而在绝大多数生物体内均受到严格管控。