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Modeling pleomorphic rhabdomyosarcoma in mice. Modeling pleomorphic rhabdomyosarcoma in mice

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA875145
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Here we used Ptch1+/-/ETV7TG/+/- mice with enhanced incidence of RMS to generate a model of pleomorphic RMS driven by haploinsufficiency of the lysosomal sialidase Neu1. These tumors share features and location with human RMS. Overall design: We compared fourteen tumor samples taken from Neu1+/−/Ptch1+/−/ETV7 TG+/− (NPE) mice with seven tumor samples from Ptch1+/−/ETV7 TG+/− (PE) mice using the Mouse ClariomS array.
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2022-08-30
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