Crystal structure of the L411A mutant of pregnane X receptor ligand binding domain in complex with SJPYT-331
收藏Protein Data Bank Japan2026-01-21 更新2026-04-19 收录
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Crystal structure of the L411A mutant of pregnane X receptor ligand binding domain in complex with SJPYT-331 Descriptor: Pregnane X receptor ligand binding domain tethered to steroid receptor coactivator-1 peptide, methyl 3-{[(1P)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carbonyl]amino}-4-{[(3S)-hexan-3-yl]oxy}benzoate Authors: Huber, A.D, Garcia-Maldonado, E, Miller, D.J, Chen, T. Deposit date: 2025-04-08 Release date: 2025-11-05 Last modified: 2026-01-21 Method: X-RAY DIFFRACTION (2.76 Å) Cite: Subtle changes in ligand-receptor interactions dramatically alter transcriptional outcomes of pregnane X receptor modulators. Structure, 34, 2026
创建时间：
2025-04-08
