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Metadata record for the article: Systemic immune reaction in axillary lymph nodes adds to tumor infiltrating lymphocytes in triple-negative breast cancer prognostication

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Figshare2021-06-15 更新2026-04-08 收录
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https://springernature.figshare.com/articles/dataset/Metadata_record_for_the_article_Systemic_immune_reaction_in_axillary_lymph_nodes_adds_to_tumor_infiltrating_lymphocytes_in_triple-negative_breast_cancer_prognostication/14589063/1
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<b>Summary</b><br> This metadata record provides details of the data supporting the claims of the related article: “Systemic immune reaction in axillary lymph nodes adds to tumor infiltrating lymphocytes in triple-negative breast cancer prognostication”. The related study aimed to capture systemic immunity, as identified by histological alterations in cancer-free lymph nodes (LNs), and determine whether this carried clinical importance. Type of data: histopathological assessment of primary tumour and LNs Subject of data: <i>Homo sapiens</i> Sample size: 161 Population characteristics: patients with invasive breast carcinoma of no special type (IBC-NST) treated between 2005 and 2010 at Tianjin Medical University Cancer Hospital, China, consisting of HR-negative patients (HER2-positive or TNBC) with positive LNs and of histological grade 3 <b>Data access</b> All data are openly available together with this data record in the file ‘LymphNodeMorphologicalAssessment_Liu.txt’ (table in tab-separated value format). The table contains count data for the assessment of morphological features of cancer-free and involved lymph nodes of hormone-receptor negative breast cancers. In addition, it lists tumor-infiltrating lymphocytes (TILs) scores, and detailed clinico-pathological data. <b>Corresponding author(s) for this study</b> Dr Anita Grigoriadis, Breast Cancer Now Unit, Innovation Hub, Cancer Center at Guy’s, Great Maze Pond, London, SE1 9RT, UK. Phone: +44 020 7188 2360. e-mail: anita.grigoriadis@kcl.ac.uk<br> <br> <b></b> <b>Study approval </b> Ethical clearance was obtained from the local research ethics committee (Medical Ethics Committee of Tianjin Medical University Cancer Institute and Hospital, Ek2020021).
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Salgado, Roberto; Wu, Kailiang; Guo, Xiaojing; E Pinder, Sarah; Grigoriadis, Anita; Hardiman, Thomas; Ng, Tony; Quist, Jelmar; Purushotham, Arnie; Liu, Fangfang; Gazinska, Patrycja
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2021-06-15
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