Genotype distribution of Lrig mutant animals.

Mice were generated from intercrosses between animals carrying Lrig1 and Lrig2 (top) or Lrig1 and Lrig3 mutant alleles (top). The number of mice carrying each genotype at postnatal day 7 (P7) and at 6 weeks is indicated, out of a total of 253 offspring from Lrig1;Lrig2 intercrosses and 181 offspring from Lrig1;Lrig3 intercrosses. For each genotype, the number of mice that is expected from this kind of intercross in indicated in parentheses. χ-squared tests confirmed that the observed distribution of genotypes is significantly different from the expected distribution.