Baseline characteristics and design features of included trials.

ACS: acute coronary syndrome; AF: atrial fibrillation; ASA: aspirin; CABG: coronary arterial bypass graft; CAD: coronary arterial disease; CVD: cerebrovascular disease; Clop: clopidogrel; Exp/Ctrl: data of the corresponding items in experimental group and control group, separately; F: female; MI: myocardial infarction; NR: not reported. TIA: transient ischemic attack. PAD: peripheral arterial disease. *Number of patients. ¶Documented cerebrovascular diseases during previous 5 years. §Risk factors for stroke: an age of 75 years or more; systemic hypertension during treatment; previous stroke, transient ischemic attack, or non–central nervous system systemic embolism; a left ventricular ejection fraction of less than 45%; peripheral vascular disease; or an age of 55 to 74 years and diabetes mellitus or coronary artery disease.