Crystal structure of factor Xa in complex with compound "1"
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Crystal structure of factor Xa in complex with compound "1" Descriptor: 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR XA Authors: Nazare, M, Will, D.W, Matter, H, Schreuder, H, Ritter, K, Urmann, M, Essrich, M, Bauer, A, Wagner, M, Czech, J, Laux, V, Wehner, V. Deposit date: 2005-04-11 Release date: 2006-04-05 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-Ray Crystallography. J.Med.Chem., 48, 2005
创建时间:
2005-04-11



