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AS-exos exacerbates microglial ferroptosis-driven neuroinflammation

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE248793
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Experimental atherosclerosis was established by feeding Apoe KO mice a Western, high-fat diet for 12 weeks and experimental cerebral ischemia was established by middle cerebral artery occlusion. RNA-seq was perfomed to investigate the potential gene regulation of AS (LAA)-exo-dependent changes of microglia. Transcriptional profiles of microglia sorted from Sham mice, MCAO mice, MCAO mice treated with Ctrl-exos, and MCAO mice treated with AS-exos.
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2024-08-16
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