RT-PCR (Gene Expression Profiling of Key Oncogenes and Tumor Suppressor Genes in Leukemia)

This study investigates the expression profiles of key oncogenes (FLT3, MYC, CXCR4, KIT) and tumor suppressor genes (TP53, RUNX1, BCR-ABL1) in leukemia patients compared to healthy controls. Using RT-qPCR, significant dysregulation of these genes was observed, highlighting their potential roles in leukemia progression. The findings suggest these genes as promising biomarkers for early diagnosis and therapeutic targets. Statistical analysis revealed significant correlations between specific genes, providing insights into their interactions in leukemia. This research contributes to understanding the molecular mechanisms of leukemia and supports the development of targeted therapies for improved patient outcomes.