tDCS, Exercise and S100B Indicated Blood Brain Barrier Permeability

This study aimed to assess the unique and combined effect of tDCS and exercise on BBB permeability, as assessed through changes in salivary S100B. It was hypothesised that active tDCS would induce a significant increase in S100B when compared to sham stimulation and no stimulation. It was also hypothesised that the increase in S100B concentration would be greater following active tDCS and exercise compared to tDCS or exercise alone. Regarding the effects of exercise, a significant increase in S100B following the cycling task was hypothesised.