This datased was used to obtain a genome-wide expression signature for the early response of mouse motor neurons to mutant SOD1 astrocytes conditioned media. Neurons, far from living in isolation, are
Structure of the mouse CD98 heavy chain ectodomain Descriptor: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, CHLORIDE ION Authors: Schiefner, A, Deuschle, F.-C, Skerra, A. Deposit date: 2018-1
Background: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive injury of both upper and lower motor neurons. Recently, protein-truncating and missens
Background It is known that in vivo human prion protein (PrP) have the tendency to form fibril deposits and are associated with infectious fatal prion diseases, while the rabbit PrP does not readily f
The reduction in ALS Functional Rating Score (ALSFRS) from reported symptom onset to diagnosis is used to estimate rate of disease progression. ALSFRS decline may be non-linear or distorted by drop-ou