Hierarchal gene master regulators of adenocarcinomic human alveolar basal epithelial cells A549.. Hierarchal gene master regulators of adenocarcinomic human alveolar basal epithelial cells A549.

In previous papers we proved that cancer nodules and surrounding normal tissue are governed by different gene master regulators (GMRs) and that expression manipulation of a cancer GMR can selectively destroy cancer cells with minimal effects on the normal ones. GMR is defined as a coding or non-coding transcript whose strictly controled abundance by the cell homeostatic mechanisms regulates most major cell functional pathways. Here, we determined the gene hierarchy in the standard adenocarcinomic human alveolar basal epithelial cell line A549. Overall design: One condition, 4 replicas