hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export IV. Homo sapiens

To define the in vivo targets of the human nuclear exosome, we performed stranded RNA-seq using rRNA-depleted RNAs isolated from HeLa cells. Overall design: rRNA-depleted RNAs isolated from control, hRRP40 or hMTR4 siRNA treated HeLa cells were generated by deep sequencing, using Illumina HiSeq 2000.