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Triple combination of BET plus pan-PI3K and NF-κB inhibitors exhibit synergistic activity in adult T cell leukemia/lymphoma

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE179307
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We exploited the use of I-BET762, copanlisib, and bardoxolone methyl inhibitors as triple combination to understand the interactions between these three pathways in Adult T cell leukemia/lymphoma. Examination of ATL43Tb (-) tumor isolated from NSG mice treated with either vehicle or Triple combination of I-BET762, Copanlisib and bardoxolone methyl.
创建时间:
2022-03-01
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