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Crystal structure of the second bromodomain of human BRD2 in complex with 4IND

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Protein Data Bank Japan2025-08-20 更新2026-04-19 收录
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Crystal structure of the second bromodomain of human BRD2 in complex with 4IND Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, Bromodomain-containing protein 2, methyl [(4S)-6-(1H-indol-4-yl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]acetate Authors: Nithianantham, S, Fischer, M. Deposit date: 2023-10-06 Release date: 2025-04-02 Last modified: 2025-08-20 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Positional isomers of Indolyl-benzodiazepines display dissimilar binding and recruitment of BET transcriptional regulators to targeted genomic loci. Bioorg.Chem., 164, 2025
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2023-10-06
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