Adult nucleus accumbens single-nucleus RNA-seq dataset for "A dopamine-induced coordinated gene expression program regulates neuronal function and cocaine response"

This dataset contains single-nucleus RNA sequencing results from adult rat brain (nucleus accumbens) and serves as the basis for characterization of transcriptional response to cocaine (20mg/kg, intraperitoneal injection). The goal of this experiment was to define the transcriptional response to cocaine across distinct cell types in the nucleus accumbens. Single-cell sequencing was carried out on FACS-sorted nuclei isolated from these experiments using the 10X Genomics Chromium single cell sequencing platform.本数据集包含成年大鼠脑伏隔核（nucleus accumbens）的单细胞核RNA测序（single-nucleus RNA sequencing）结果，可为解析可卡因（20mg/kg，腹腔注射）处理后的转录应答特征提供依据。本实验的目标是阐明伏隔核内不同细胞类型对可卡因的转录应答特征。本研究采用10X Genomics Chromium单细胞测序平台，对从该实验中分离得到的经荧光激活细胞分选（FACS）处理的细胞核开展了测序工作。