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Integrated Genomic and Transcriptomic Analysis of Small Cell Lung Cancer Reveals Inter- and Intratumoral Heterogeneity and a Novel Chemotherapy-Refractory Subtype

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NIAID Data Ecosystem2026-04-29 收录
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https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs002541.v1.p1
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We evaluated 100 small cell neuroendocrine cancers (SCNC) acquired by biopsies from 72 patients, including 62 patients with SCLC and 10 patients with extrapulmonary small cell cancer (EPSCC) who enrolled in either clinical trials of NCT02487095, NCT02484404, and/or NCT02146170. ]]> The primary and secondary outcomes of the clinical trial were related to anti-tumor efficacy of the combination, and are described in detail in the clinical trial reported previously (PMIDs: 31063862 and 33848478).]]>
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2021-08-04
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