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Data: Gene expression of Mowat-Wilson syndrome patient derived GABAergic interneurons

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DataCite Commons2025-01-16 更新2025-04-16 收录
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IPSC lines established from fibroblasts of both sibling (MW1=26, MW2=27) and two healthy donors (Ctl2=K02 and Ctl8=K08). <br> Neurocortical differentiation of iPSCs (samples IPS) was carried out as described using Dual-SMAD inhibition that promotes conversion into neural stem cells (NSC) for 10 days (samples INT) followed by directed differentiation into cortical lineages for 65 days (samples D65). <br> Bulk RNA sequencing reads were aligned to the ENSEMBL human reference genome (Homo_sapiens.GRCh37.75) and gene counts were generated using the STAR read aligner. The count data is not normalized and can be used with DESEq2. <br> Expression data was generated for all three time points IPS -&gt; INT (D10) -&gt; D65 <br> File names are: timepoint_SampleReadsPerGene.out.tab

提供机构:
Uppsala University
创建时间:
2022-08-11
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