Regulation of mRNA translation by RNH1 in hematopoietic cells. Regulation of mRNA translation by RNH1 in hematopoietic cells
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA994104
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资源简介：
Ribonuclease Inhibitor (RI also known as Rnh1) is a 50 kDa, ubiquitously expressed leucine-rich repeat (LRR) containing protein. It binds to pancreatic-type ribonucleases and inhibit their function. However, the entire biological role of Rnh1 is unknown. We generated RNH1 knock out K562 cells by CRISPR/Cas9 method. We isolated polysomal RNA from control and RNH1-deficient K562 cells to quantify actively translated mRNAs by RNA-seq. Overall design: Total RNA was isolated from polysome fractions of wild type and RNH1 deficient K562 cells.
创建时间：
2023-07-12
