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co-crystal structure of MDM2(17-111) in complex with compound 48

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Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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co-crystal structure of MDM2(17-111) in complex with compound 48 Descriptor: E3 ubiquitin-protein ligase Mdm2, [(2R,5R,6R)-4-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-6-(3-chlorophenyl)-5-(4-chlorophenyl)-3-oxomorpholin-2-yl]acetic acid Authors: Huang, X. Deposit date: 2014-01-08 Release date: 2014-04-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres. J.Med.Chem., 57, 2014
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2014-01-08
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