Aging leads to a gradual decline in physical activity and disrupted energy homeostasis. The NAD+-dependent SIRT6 deacylase regulates aging and metabolism through mechanisms that largely remain unknown

NIAID Data Ecosystem90

衰老生物学

代谢基因调控

In living organisms, ageing is widely considered to be the result of a multifaceted process consisting of the progressive accumulation of damage over time, having implications both in terms of functio

Figshare2016-08-13 更新60

衰老生物学

Wnt信号通路

Purpose: Characterize functional alterations in stem cells and paneth cells obtained from young and aged mice, focusing on age-based impairment of intestinal regeneration due to a decline in canonical

NIAID Data Ecosystem100

Gene expression analysis of cell populations derived from skeletal muscle of young and aged mice

衰老生物学

骨骼肌细胞分化

Comprehensive analyses of mRNA expression were performed using three different cell populations isolated from skeletal muscle of young and aged mice to investigate age-related changes of each cell pop

NIAID Data Ecosystem70

Peroxiredoxin regulates DAF-16/FOXO mediated mitochondrial remodelling in response to exercise that is disrupted in ageing

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