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KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP270313
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资源简介:
The goal of this study was to define functional and gene regulatory effects of KDM3A and Ets1, and their relationship to the PAX3/FOXO1 driver oncofusion, in fusion-positive Rhabdomyosarcoma. Overall design: RNA-seq was used to define the effects of KDM3A and Ets1 shRNA-mediated depletion on gene expression in the patient-derived fusion-positive Rhabdomyosarcoma cell lines Rh41 and Rh30.
创建时间:
2023-01-11
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