Structure of Ack1 kinase in complex with a selective inhibitor
收藏Protein Data Bank Japan2023-10-25 更新2026-03-21 收录
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Structure of Ack1 kinase in complex with a selective inhibitor Descriptor: 5-chloro-N~2~-[4-(4-methylpiperazin-1-yl)phenyl]-N~4~-{[(2R)-oxolan-2-yl]methyl}pyrimidine-2,4-diamine, Activated CDC42 kinase 1, CHLORIDE ION Authors: Thakur, M.K, Miller, W.T, Mahajan, N, Seeliger, M.A. Deposit date: 2020-11-10 Release date: 2022-02-09 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Inhibiting ACK1-mediated phosphorylation of C-terminal Src kinase counteracts prostate cancer immune checkpoint blockade resistance. Nat Commun, 13, 2022
创建时间：
2020-11-10
