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Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Novel fluoroquinolones in complex with topoisomerase IV from S. pneumoniae and E-site G-gate Descriptor: (3aS,4R)-4-amino-13-cyclopropyl-8-fluoro-10-oxo-3a,4,5,6,10,13-hexahydro-1H,3H-pyrrolo[2',1':3,4][1,4]oxazepino[5,6-h]quinoline-11-carboxylic acid, E-site1, E-site2, ... Authors: Laponogov, I, Pan, X.-S, Vesekov, D.A, Cirz, R.T, Wagman, A.S, Moser, H.E, Fisher, L.M, Sanderson, M.R. Deposit date: 2013-05-13 Release date: 2014-11-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.24 Å) Cite: Exploring the active site of the Streptococcus pneumoniae topoisomerase IV-DNA cleavage complex with novel 7,8-bridged fluoroquinolones. Open Biol, 6, 2016
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2013-05-13
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