The Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [expression]

ChEBI2013-06-04 更新2026-07-21 收录

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肿瘤抑制基因

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The Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [expression]

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2013-06-04

The nucleosomal barrier to promoter escape by RNA Polymerase II is overcome by the chromatin remodeler Chd1 [HiSeq]. Mus musculus

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核小体周转

We use a metabolic labeling strategy for directly measuring nucleosome turnover to determine the role of chromatin remodeler Chd1 on chromatin dynamics in mouse embryonic fibroblasts expressing with w

NIAID Data Ecosystem90

The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats

R-loop调控

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ATRX is a chromatin remodelling factor found at a wide range of tandemly repeated sequences including telomeres (TTAGGG)n. Acquired mutations in ATRX are found in nearly all tumours which maintain the

NIAID Data Ecosystem50

The histone variant H2A.Z in yeast is almost exclusively incorporated into the +1 nucleosome in the direction of transcription

组蛋白变体定位

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To investigate the incorporation dynamics of histone variant H2A.Z, we determined its genomic localization at single nucleosome resolution, as well as the localization of its chromatin remodelers Swr1

NIAID Data Ecosystem40

The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and transcription start site selection in Arabidopsis [RNA-seq]. The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and transcription start site selection in Arabidopsis [RNA-seq]

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RNA测序

In eukaryotes, DNA is associated with histones to form nucleosomes, the basic component of the chromatin. This structure presents a physical barrier for nuclear proteins to access DNA and, therefore,

NIAID Data Ecosystem70

Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A.Z deposition. [RNA-Seq]

植物表观遗传学

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Deposition of histone variant H2A.Z by the SWR1 chromatin-remodeling complex is critical for the appropriate expression of many genes in eukaryotes, yet, despite its importance, the composition of the

NIAID Data Ecosystem50

The Swi/Snf tumor suppressor complex establishes nucleosome occupancy at target promoters [expression]

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