Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) Complex with Azapeptide Inhibitor 20a
收藏Protein Data Bank Japan2025-10-08 更新2026-04-04 收录
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Crystal Structure of SARS-CoV-2 Omicron Main Protease (Mpro) Complex with Azapeptide Inhibitor 20a Descriptor: 3C-like proteinase nsp5, N-[(2S)-1-{2-(dichloroacetyl)-2-[(2-oxo-1,2-dihydropyridin-3-yl)methyl]hydrazin-1-yl}-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide Authors: Vishwakarma, J, Taylor, A.B, Harris, R.S. Deposit date: 2024-12-05 Release date: 2025-09-24 Last modified: 2025-10-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity. J.Med.Chem., 68, 2025
创建时间:
2024-12-05



