Transcriptomic study of NR8383 rat macrophages cells following exposure to TiO2 (NM105, p25 anatase/rutile)

To identify differentially expressed genes and key biological pathways that define toxicity following nanomaterial exposure, we performed microarray analyses on NR8383 macrophages exposed for 4 h to 3 cm²/cm² of TiO2 (NM105, p25 anatase/rutile). This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement N°. 686098为鉴定纳米材料暴露后介导毒性的差异表达基因与关键生物通路，我们对暴露于3 cm²/cm²二氧化钛(TiO2，NM105，p25锐钛矿/金红石型)的NR8383巨噬细胞开展了4小时的基因芯片分析。本项目已获得欧盟“地平线2020”研究与创新计划的资助，资助协议编号为686098。