WP5336 - Induction of autophagy and toll-like receptor signaling by graphene oxide - Homo sapiens
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Graphene oxide has been found in the RAW264.7 to trigger a cytokine response and resulting autophagy. It was found to be mediated by activation of TLR4 and TLR9, signalling MyD88, TRAF6, and NF-κB, resulting in cytokine expression. However, TLR signaling did not cause IFN-β expression nor IRF3 activation. The process also shows activation of Beclin 1 and LC3.
创建时间：
2025-04-17
