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Homo sapiens bulk RNA-seq

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP663083
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资源简介:
This study investigates the role of cGAS signaling in amyotrophic lateral sclerosis using human iPSC-derived microglia-motor neuron co-cultures and TDP-43 Q331K mouse models. Bulk RNA sequencing and single-nucleus RNA sequencing were performed to assess transcriptional and RNA splicing changes associated with TDP-43 pathology and their modulation by pharmacological cGAS inhibition.
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2026-02-12
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