Whole genome sequencing of multidrug-resistant Pseudomonas aeruginosa strains

Multidrug-resistant Pseudomonas aeruginosa remains a major cause of healthcare-associated infections, particularly in high-burden clinical settings, where rapid toolscapable of capturing clinically relevant resistance and virulence phenotypes are urgentlyneeded. In this study, we applied an integrated whole genome sequencing (WGS) andFourier-transform infrared (FTIR) spectroscopy approach to evaluategenotype-phenotype relationships in multidrug-resistant P. aeruginosa isolates collectedduring the COVID-19 pandemic.