Cancer Cell Line Encyclopedia
收藏知名数据库2026-06-26 收录
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https://sites.broadinstitute.org/ccle/
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资源简介:
Cancer Cell Line Encyclopedia (CCLE) 是一个大型癌症细胞系数据库,旨在对人类癌细胞模型进行详细的遗传和药理学表征。该数据库包含约1000种癌细胞系的基因组、转录组和药物敏感性数据,用于研究癌症生物学、验证癌症靶点和定义药物疗效。CCLE项目分为三个阶段,不断扩展和完善对癌细胞系的表征,包括基因组、转录组、蛋白质组和代谢组等多维度数据。
Cancer Cell Line Encyclopedia (CCLE) is a large-scale cancer cell line database dedicated to the detailed genetic and pharmacological characterization of human cancer cell models. This database contains genomic, transcriptomic and drug sensitivity data for approximately 1,000 cancer cell lines, which is utilized for research into cancer biology, validation of cancer targets and definition of drug efficacy. The CCLE project is divided into three phases, continuously expanding and refining the characterization of cancer cell lines, including multi-dimensional data such as genomics, transcriptomics, proteomics and metabolomics.



