Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir)
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Crystal structure of M46L mutant of HIV-1 protease complexed with TMC114 (darunavir) Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Weber, I.T, Kovalevsky, A.Y, Liu, F. Deposit date: 2006-07-20 Release date: 2006-10-03 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.22 Å) Cite: Ultra-high Resolution Crystal Structure of HIV-1 Protease Mutant Reveals Two Binding Sites for Clinical Inhibitor TMC114. J.Mol.Biol., 363, 2006
创建时间：
2006-07-20
