Ras:SOS:Ras in complex with a small molecule activator
收藏Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Ras:SOS:Ras in complex with a small molecule activator Descriptor: (2S)-2-amino-1-[(3aR,6aS)-5-[(5-chloro-1H-indol-3-yl)methyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl]-3-(1H-indol-3-yl)propan-1-one, FORMIC ACID, GLYCEROL, ... Authors: Phan, J, Abbott, J, Fesik, S.W. Deposit date: 2017-12-13 Release date: 2018-10-24 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.796 Å) Cite: Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling. J. Med. Chem., 61, 2018
创建时间:
2017-12-13



